Anxiety, depression and health-related quality of life in adult liver transplant recipients with different survival periods

  • Status
    The poster was presented at the 28th Annual Conference of the International Society for Quality of Life Research in October 2021


Method: A internet questionnaire was used to investigate 290 cases from 17 February to 14 March 2020. Hospital Anxiety and Depression Scale (HADS) was used to evaluate anxiety and depression. The HRQoL assessment used the physical component summary (PCS) and mental component summary (MCS) scores of the Medical Outcomes Study Short-Form 36 Health Survey (SF-36) and the SF-6D utility value.

①Four groups of patients, representing 0.25 years, 1 year, 5 years, and 10 years after transplantation were studied. No statistically significant differences were found in gender, marital status, and culture group (P>0.05), and the age difference was statistically significant (P<0.05).②The scores of anxiety and depression were (5.45±2.75 VS. 4.64±3.19 VS. 4.78±3.73 VS. 3.16±3.63, F=3.54, P<0.05) and (4.82±3.84 VS. 3.72±3.42 VS. 3.72 ±3.25 VS. 3.43 ±4.30, F=0.79, P>0.05) among them. Comparisons showed that the scores of anxiety in the 10-year group were significantly lower than the other 3 groups.③The scores of PCS and MCS scores were (57.86±17.94 VS. 74.96±15.54 VS. 75.10±18.08 VS. 77.38±19.90, F=7.39, P<0.001) and (56.64±19.58 VS. 73.91±16.85 VS. 73.84±15.93 VS. 78.23±21.28, F=7.88, P<0.001), SF-6D utility value were (0.64±0.10 VS. 0.76±0.10 VS. 0.74±0.13 VS. 0.79±0.15, F=7.61, P<0.001). The PCS, MCS, and SF-6D scores of the 0.25-year group were significantly lower than the other 3 groups.

Conclusion: Those who survive longer after liver transplant may experience lower levels of anxiety and higher levels of health-related quality of life. Special attention should be paid to relieving anxiety and improving health-related quality of life for patients with short postoperative stays.